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. 2019 Sep 13;110(6):1404–1415. doi: 10.1093/ajcn/nqz220

TABLE 2.

Characteristics of the study's participants organized by vitamin K abundance clusters1

Mean ± SD Cluster vs. cluster P2
Characteristic Cluster 1 (n = 11) Cluster 2 (n = 29) Cluster 3 (n = 11) Cluster 4 (n = 15) P 3 1 vs. 2 1 vs. 3 1 vs. 4 2 vs. 3 2 vs. 4 3 vs. 4
MMSE score 15 ± 9.7 23 ± 7.5 27 ± 4.6 26 ± 4 0.0013 0.0353 <0.0013 0.0012 0.0322 0.123 0.272
Age, y 85 ± 7.4 80 ± 9.6 76 ± 8.3 75 ± 6.8 0.0193 0.121 0.0152 0.0102 0.100 0.118 0.400
Barthel score 8.3 ± 6.5 14.7 ± 7.1 17.4 ± 4.9 18.5 ± 3.6 <0.0013 0.025 2 <0.0012 0.0422 <0.0012 0.0392 0.323
No. of hypertension medications 0.18 ± 0.4 0.53 ± 0.9 0.45 ± 0.9 0.27 ± 0.6 0.759 1.000 0.508 0.433 0.471 0.594 0.480
No. of diabetes medications 0 ± 0 0.21 ± 0.5 0.07 ± 0.3 0 ± 0 <0.0013 0.105 0.396 0.500 0.0712 0.140 0.469
No. of diagnoses 5.9 ± 2.9 3.7 ± 2 2.2 ± 1.8 2.8 ± 2 0.0013 0.090 0.0012 0.0122 0.0142 0.112 0.188
No. of drugs 6.3 ± 3.2 4.7 ± 2.9 4.8 ± 3.6 4.8 ± 1.9 0.339 0.199 0.220 0.413 0.221 0.485 0.480
Serum PK, nmol/L 0.82 ± 08 0.86 ± 0.8 1.18 ± 1.5 0.73 ± 0.5 0.043 0.582 0.347 0.489 0.720 0.706 0.468
TNF-α, IU 7.89 ± 3.7 9.97 ± 12.5 4.79 ± 1.9 5.64 ± 2.8 0.0333 0.177 0.0182 0.083 0.091 0.240 0.191
IL-6, IU 13.13 ± 12.7 28.08 ± 51.1 5.96 ± 3.5 17.67 ± 42.8 0.0253 0.351 0.101 0.221 0.0132 0.087 0.252
IL-8, IU 25.56 ± 17.5 18.59 ± 8.4 20.38 ± 26.4 14.42 ± 7.8 0.198 0.2392 0.2003 0.1318 0.2237 0.1486 0.2878
Diversity: Shannon index 3.04 ± 0.4 3.53 ± 0.3 3.79 ± 0.5 3.55 ± 0.6 0.0013 0.0172 <0.0012 0.0182 0.0512 0.499 0.058
BMI, kg/m2 23.7 ± 5.8 27 ± 4.5 26.5 ± 5.8 29.8 ± 8.8 0.123 0.047 0.083 0.290 0.091 0.439 0.316
1

Values are means ± SD. Individual values can be found in Supplemental Table 7. MMSE, Mini-Mental State Examination; PK, phylloquinone.

2

P < 0.05, Dunn post hoc test for pairwise comparisons.

3

< 0.05, Kruskal-Wallis test.