TABLE 4.
Association of each variable in the Poisson statistical model with MMSE1
| Variable | eRC | 2.5%, 97.5% CI | P value |
|---|---|---|---|
| Age, y | 1 | 0.98, 1.02 | 0.98 |
| Cluster 2 (n = 19) | 0.58 | 0.38, 0.89 | 0.0132 |
| Cluster 3 (n = 29) | 0.54 | 0.33, 0.89 | 0.0172 |
| Cluster 4 (n = 15) | 0.83 | 0.51, 1.37 | 0.47 |
| Strata (day hospital) (n = 9) | 1.32 | 0.59, 2.77 | 0.48 |
| Strata (long stay) (n = 17) | 3.38 | 1.51, 7.55 | 0.0032 |
| Strata (rehab) (n = 7) | 3.15 | 1.59, 6.26 | <0.0012 |
| Gender (male) (n = 23) | 0.89 | 0.62, 1.27 | 0.52 |
| Barthel score | 0.98 | 0.93, 1.03 | 0.49 |
| No. of diagnoses | 0.91 | 0.83, 1 | 0.0492 |
| No. of drugs | 0.98 | 0.91, 1.05 | 0.48 |
| Presence of hypertension (n = 23) | 0.87 | 0.54, 1.38 | 0.58 |
| Hypertension, 1 medication (n = 8) | 0.83 | 0.47, 1.47 | 0.52 |
| Hypertension, 2 medications, (n = 6) | 1.55 | 0.69, 3.42 | 0.28 |
| Hypertension, 3 medications, (n = 3) | 0.55 | 0.08, 2.07 | 0.45 |
| Presence of diabetes (n = 5) | 4.17 | 0.58, 32.46 | 0.16 |
| Diabetes, 1 medication (n = 2) | 0.26 | 0.03, 2.02 | 0.21 |
| Diabetes, 2 medications (n = 2) | 0.31 | 0.03, 3.26 | 0.33 |
| Serum PK, nmol/L | 0.93 | 0.65, 1.25 | 0.64 |
| TNF-α, IU | 0.99 | 0.95, 1.04 | 0.73 |
| IL-6, IU | 1.01 | 1, 1.01 | 0.055 |
| IL-8, IU | 1 | 0.99, 1 | 0.61 |
| Diversity: Shannon index | 0.74 | 0.5, 1.11 | 0.14 |
| BMI, kg/m2 | 0.99 | 0.95, 1.02 | 0.4 |
| Antidepressants/antipsychotics (n = 20) | 1.52 | 0.97, 2.38 | 0.066 |
1
Association between the vitamin K clusters and MMSE after adjusting for age; Barthel score; presence of hypertension and diabetes; number of cardiovascular and diabetes medications; polypharmacy; multimorbidity; concentrations of serum PK, TNF-α, IL-6, and IL-8; Shannon diversity; BMI; antipsychotic medications; gender; and strata. eRC, exponentiated regression coefficient; MMSE, Mini-Mental State Examination; PK, phylloquinone.
2
P < 0.05, Poisson regression model.