Fig. 1.

mRNA expression and DNA methylation status of SATB2 and NRG1 genes in multiple paired samples of uterine leiomyoma and adjacent normal myometrium. aSATB2 and NRG1 mRNA expression which was analyzed by RT-PCR in triplicates in the 11 paired samples of uterine leiomyoma (L) and adjacent normal myometrium (M). GAPDH was used as an internal control. b Relative expression levels of SATB2 and NRG1 mRNA to GAPDH. Values are mean ± SD. c DNA methylation levels of SATB2 and NRG1 genes in the 11 paired samples of uterine leiomyoma and adjacent normal myometrium were evaluated in triplicates by combined bisulfite restriction analysis (COBRA). Values are mean ± SD