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. 2019 Dec 2;10(12):908. doi: 10.1038/s41419-019-2138-4

Fig. 4. miR-9 attenuates ischemic injury of MI mice.

Fig. 4

a Representative images of cross section slices showing infarct areas in MI (3 day) mice (scale bar: 3 mm). b Statistical analysis of IA/LV ratio. IA: infarct area; LV: left ventricle (n = 5). **P < 0.01 by Student’s t-test. c Representative M-mode echocardiographic tracings in MI (3 day) mice (time scale for X-axis: 100 ms; scale bar for Y-axis: 2 mm). Data are presented as mean ± SEM. d Ejection fraction (EF) and e Fractional shortening (FS) (n = 5). *P < 0.05, **P < 0.01 by one-way ANOVA analysis with Tukey’s multiple comparison test. Data are presented as mean ± SEM. f Effects of agomiR-9 on serum lactate dehydrogenase (LDH) activity in MI (3 day) mice (n = 5). **P < 0.01 by one-way ANOVA analysis with Tukey’s multiple comparison test. Data are presented as mean ± SEM. g Inhibition of caspase-3 activity by agomiR-9 in MI (3 day) mice (n = 5). **P < 0.01 by one-way ANOVA analysis with Tukey’s multiple comparison test. Data are presented as mean ± SEM. h Effects of agomiR-9 on cardiac apoptosis evaluated by TUNEL staining in MI (3 day) mice (scale bar: 60 μm). i The percentage of TUNEL-positive cell in different groups (n = 5). *P < 0.05, **P < 0.01 by one-way ANOVA analysis with Tukey’s multiple comparison test. Data are presented as mean ± SEM.