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Effects of heterologous mouse mitochondrial transcription factor A (mTFAM) overexpression in HeLa cells. HeLa cells were transduced with rv.2739 and lv.4054 for doxycycline-regulated expression of mTFAM cDNA, and mitochondrial parameters were followed during induction. (A) mTFAM transcript. (B) mtDNA transcripts. (C) Protein levels. (D) mtDNA content. (E) Mitochondrial mass. *p < 0.05; **p < 0.01; ***p < 0.001.
