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TSG101 promotes mitochondrial fission and biogenesis upon endotoxin challenge. A–E, Western blots and quantification analysis (A) showing the protein expression of Mfn1 (B), Mfn2 (C), Drp1 (D), and PGC-1a (E) in hearts of WT and TG mice subjected to endotoxin injection for 6 h. GAPDH was used as a loading control for total protein. n = 6 for each group. * and #, p < 0.05 versus PBS WT; &, p < 0.05 versus PBS TG; $, p < 0.05 versus LPS WT.
