Figure 1.

A, schematic diagram of the modular structure of Dp0100 and its truncation mutants. B, phylogenetic analysis of the catalytic domain of Dp0100 (TM5) and its close relatives from PL8, PL15, PL17, and PL21. The percentage of replicate trees in which the associated taxa clustered together in the bootstrap test (1000 replicates) is shown next to the branches (57). The tree is drawn to scale, with branch lengths in the same units as those of the evolutionary distances used to infer the phylogenetic tree.