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. 2019 Oct 22;4(4):599–608. doi: 10.1002/epi4.12364

Table 1.

Overview of demographic and clinical characteristics of the patients who suffered from TCS during video‐EEG monitoring who were included

Demographic parameters Category N Percent
Sex Female 17 53.1
Male 15 46.9
Epileptogenic zone Temporal 17 53.1
Frontal 4 12.5
Parietal 1 3.1
Hemispheric 2 6.3
Multifocal 2 6.3
Generalized 6 18.8
Etiology Unknown 11 34.4
Genetic/idiopathic generalized 6 18.8
Hippocampal sclerosis 4 12.5
Disorders of cortical development 6 18.8
Benign tumor 2 6.3
Postinfectious 2 6.3
Vascular 1 3.1
TCS types Type I—bilateral symmetric tonic arm extension 4 10.3
Type II—clonic without tonic extension 2 5.1
Type III—asymmetric or bilateral tonic arm flexion 33 84.6
Wake state Asleep 20 51.3
Awake 19 48.7
Postictal EEG Alpha 2 5.1
Diffuse slowing 19 48.7
PGES 17 43.6
Undeterminable due to artifacts 1 2.6

The different TCS subtypes were recently defined by Alexandre et al.17

Type I: Typical tonic‐clonic seizure with bilateral and symmetric tonic arm extension at the onset of secondary generalization, followed by bilateral and symmetric 4‐limb myoclonic jerk.

Type II: Clonic seizure with bilateral and symmetric 4‐limb myoclonic jerks without tonic arm extension or flexion.

Type III: Tonic‐clonic seizure with asymmetric bilateral tonic arm extension, unilateral tonic arm extension combined with contralateral tonic arm flexion, bilateral tonic arm flexion, or unilateral tonic arm extension, followed by bilateral and symmetric 4‐limb myoclonic jerks and TCS in which the onset was not clear due to blankets covering the camera view, etc.