Figure 4.

Neurite outgrowth of dorsal rood ganglion (DRG) neurons was elongated by ranirestat. Ranirestat (1 μmol/l) increased total neurite length in each neuron. (a) Representative figure of murine DRG neurons cultured with control medium. (b) Representative figure of mouse DRG neurons cultured with 1 μg/l ranirestat. Scale bar: 200 μm. (c) Quantified data of neurite outgrowth in mouse DRG culture. (d) Quantified data of neurite outgrowth in rat DRG culture. ctrl: control medium; rani: medium supplemented with 1 μmol/l ranirestat. ^∗p < 0.05 versus ctrl. n = 10 in each group.