Table 1.
Body weight and blood glucose levels in nondiabetic and diabetic rats.
| Nondiabetic rats | Diabetic rats | |||||
|---|---|---|---|---|---|---|
| Pre-Tx | Post-Tx | Pre-Tx | Post-Tx | |||
| Placebo | Rani | Placebo | Rani | |||
| Number | 19-20 | 4-6 | 8 | 16 | 5 | 7 |
| CBG (mM) | 6.7 ± 1.3 | 16.8 ± 4.6† | 13.2 ± 2.9† | 28.3 ± 3.9∗ | 29.6 ± 4.9∗ | 30.5 ± 4.1∗ |
| BW (g) | 518 ± 32 | 566 ± 35 | 485 ± 96 | 254 ± 54∗ | 241 ± 34∗ | 253 ± 67∗ |
Results are means ± SD. Tx: treatment; Rani: ranirestat; CBG: casual blood glucose; BW: body weight. ∗p < 0.05 versus pre-Tx nondiabetic rats and †p < 0.05 versus pre-Tx nondiabetic rats.