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Schematic structure of MYOF. MYOF has seven C2 domains, a Ferlin A domain, a DysF domain as well as a single C-terminal transmembrane helix. C2-domains are responsible for Ca2+-dependent lipid binding and interacting with targeting proteins. FerA binds to phospholipids in a Ca2+ independent manner. DysF is possibly responsible for receptor-mediated endocytosis.
