Table 1.

Association of WBP5 expression with clinicopathological factors in 131 PTC patients.

Variables	WBP5		P
	Low (n = 75)	High (n = 56)
Age (years)
<55	65	52	0.257
≥55	10	4
Gender
Men	18	11	0.301
Women	47	45
Histological variants
PTC
Classical variant	63	52	0.054
Follicular variant (infiltrative)	12	3
Solid variant	0	1
Bilaterality
Unilateral	53	48	0.043∗
Bilateral	22	8
Tumor number
Solitary	47	43	0.085
Multiple	28	13
Maximal tumor diameter
<1 (cm)	17	21	0.111
1~4 (cm)	51	33
>4 (cm)	7	2
Caspsule invasion
Absent	33	37	0.042∗
Present	10	4
Extracapsular	32	15
Intrathyroidal dissemination
Absent	61	50	0.211
Present	14	6
T staging
pT1	35	35	0.195
pT2	6	4
pT3	18	12
pT4	16	5
N staging
pN0/Nx	24	29	0.026∗
pN1a	29	20
pN1b	22	7
M staging
M0	74	54	0.797
M1	1	2
TNM staging
Ⅰ	67	54	0.562
Ⅱ	6	2
Ⅲ	1	0
Ⅳ	1	0
Total thyroidectomy
Not done	49	46	0.033∗
Done	26	10
Lymph node dissection
Not done	9	4	0.261
CCND only	35	34
CCND with MRND	31	18
Iodine radiotherapy
Not done	47	52	0∗
Done	28	4
Recurrence of disease
Absent	58	53	0.006∗
Present	17	3

^aPTC, papillary thyroid carcinoma, ^bCCND, central compartment node dissection, ^cMRND, modified radical neck dissection, ^∗Significantly different by the χ² test.