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Effects of CD47 deficiency on cardiac remodeling-related signaling pathways. (a) Representative Western blots depicting the protein levels of AMPK, p-AMPK, HDAC3, cleaved Caspase-3, cleaved Caspase-9, LC3 II, Beclin-1, p62, and LAMP2 in heart tissue. (b) The protein expression levels were quantitatively analyzed (n = 6). All data are expressed as the mean ± SD. Statistical significance: ∗P < 0.05 and ∗∗P < 0.01 versus the CD47+/+ group; #P < 0.05 and ##P < 0.01 versus the ISO group.
