Table 4.
SES factors associated with RFS in ASCC
| SES factor or covariate | Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|---|
| HR | 95% CI | P‐value | HR | 95% CI | P‐value | |
| Primary payer | ||||||
| Private | Ref. | Ref. | ||||
| Medicaid | 4.3 | 1.2‐14.9 | 0.021 | 2.9 | 0.8‐10.5 | .110 |
| Medicare | 3.4 | 0.8‐13.6 | 0.084 | 3.1 | 0.8‐12.4 | .112 |
| Race | ||||||
| Majority | Ref. | Ref. | ||||
| Minority | 3.6 | 1.7‐7.7 | 0.001 | 2.7 | 1.1‐6.5 | .030 |
| Income level | ||||||
| Upper | Ref. | |||||
| Low | 2.5 | 0.7‐8.5 | 0.147 | |||
| Middle | 1.4 | 0.4‐4.5 | 0.590 | |||
| Employment status | ||||||
| Employed or retired | Ref. | |||||
| Unemployed or disabled | 1.8 | 0.8‐3.9 | 0.150 | |||
| Partnership status | ||||||
| Partnered | Ref. | |||||
| Unpartnered | 1.7 | 0.7‐4.3 | 0.244 | |||
| Age | 1.0 | 1.0‐1.0 | 0.980 | |||
| Gender | ||||||
| Male | Ref. | |||||
| Female | 0.6 | 0.2‐1.4 | 0.239 | |||
| TN Stage | ||||||
| T1/T2, N‐negative | Ref. | Ref. | ||||
| T1/T2, N‐positive and T3/T4, N‐negative | 3.1 | 1.2‐8.0 | 0.024 | 3.2 | 1.2‐8.8 | .022 |
| T3/T4, N‐positive | 6.1 | 2.1‐17.3 | 0.001 | 4.4 | 1.4‐13.0 | .009 |
| HIV Status | ||||||
| HIV‐negative | Ref. | |||||
| HIV‐positive | 1.9 | 0.9‐3.9 | 0.099 | |||
Unadjusted and adjusted hazard ratios were calculated using Cox regression. Variables significant at P < .05 in univariate analysis were included in the multivariate model.
Abbreviations: ASCC, anal squamous cell carcinoma; CI, confidence interval; HR, hazard ratio; RFS, relapse‐free survival; SES, socioeconomic status; TN, tumor‐node.