Figure 1.

Therapeutic effect of DFP‐10825 on a MKN45 peritoneally disseminated mouse model. MKN45 peritoneally disseminated model mice were intraperitoneally injected with five injections of DFP‐10825 (2.5, 5, 10, or 20 µg thymidylate synthase [TS] short hairpin RNA [shRNA]/mouse/d) twice weekly from Day 7 post‐tumor implantation. A, Survival periods for the mice were monitored daily (n = 9‐10). B, Body weight changes of the mice were monitored twice weekly. The data are represented as the mean ± SD