Table 1.
Treatment | Doses | MST (d) | ILS (%) |
---|---|---|---|
Control | — | 48.9 ± 3.5 | — |
DFP‐10825 | 2.5 µg TS shRNA | 49.3 ± 3.9 | 0.8 |
5.0 µg TS shRNA | 52.8 ± 3.6 | 8.0 | |
10 µg TS shRNA | 53.6 ± 3.9 | 9.6 | |
20 µg TS shRNA | 56.6 ± 4.2**,$$ | 15.7 |
MST (d) and ILS (%) were determined from the data shown in Figure 1A. The MSTs are represented as the mean ± SD (n = 9‐10, **P < .01 vs control, $$ P < .01 vs 2.5 µg TS shRNA). The ILSs were calculated using a formula described in Section 2.
Abbreviations: ILS, increased life span; MST, mean survival time; TS, thymidylate synthase.