Figure 2.

Kaplan‐Meier survival curves for the spatial distribution of programmed cell death 1 (PD‐1) and CD8 tumor‐infiltrating lymphocytes in lung adenocarcinoma (LAC) and squamous cell carcinoma (SCC). The correlation analysis between PD‐1⁺ cells and CD8⁺ T cells in the tumor islets and stroma of LAC (A) and SCC (B) samples. (C) LAC patients with a high density of PD‐1⁺ cells in the both tumor islets and stroma had a shorter survival. (D) SCC patients with a high density of PD‐1⁺ cells in the both tumor islets and stroma had a longer survival. High number of CD8⁺ T cells in the both tumor islets and stroma was associated with a poor prognosis in LAC patients (E), but with a better outcome in SCC patients (F). P‐values were calculated using the log‐rank test