Figure 5.

Kaplan‐Meier survival curves for tumor microenvironment immune types (TMIT) classification in lung adenocarcinoma (LAC) and squamous cell carcinoma (SCC) samples. A, Schematic presentation of analysis of TMIT based on tumor cell programmed cell death ligand 1 (PD‐L1) expression and tumor‐infiltrating lymphocytes (TIL) infiltrating in the tumor islets or stroma. B, Representative images of immunohistochemical staining showing four types of TMIT in SCC: TMIT I (PD‐L1^high and CD8⁺ TIL^high), TMIT II (PD‐L1^low and CD8⁺ TIL^low), TMIT III (PD‐L1^high and CD8⁺ TIL^low), and TMIT IV (PD‐L1^low and CD8⁺ TIL^high). LAC patients with TMIT III (C) and SCC patients with TMIT I (D) having the longest survival, respectively. P‐values were calculated using the log‐rank test