Table 1.
Correlation of clinicopathological features with ZNRD1 expression in ZZU HCC cohort
| Clinicopathological variables features | ZNRD1 expression | P‐value | |
|---|---|---|---|
| Low expression (n = 149) | High expression (n = 192) | ||
| Age (y) | |||
| ≤50 | 51 (34.2) | 75 (39.0) | .359 |
| >50 | 98 (65.8) | 117 (61.0) | |
| Gender | |||
| Male | 120 (80.5) | 145 (80.1) | .270 |
| Female | 29 (19.5) | 47 (19.9) | |
| Pathogenesis | |||
| Virus | 110 (73.8) | 145 (75.5) | .721 |
| Others | 39 (26.2) | 47 (24.5) | |
| Cirrhosis | |||
| Absent | 135 (90.6) | 180 (93.8) | .278 |
| Present | 14 (9.4) | 12 (6.2) | |
| AFP | |||
| ≤20 | 90 (60.4) | 76 (39.6) | .000 |
| >20 | 59 (39.6) | 116 (60.4) | |
| Portal vein thrombosis | |||
| Absent | 129 (86.6) | 140 (72.9) | .002 |
| Present | 20 (13.4) | 52 (27.1) | |
| TNM stage | |||
| Stage I and II | 126 (84.6) | 137 (71.4) | .004 |
| Stage III and IV | 23 (15.4) | 55 (28.6) | |
| Tumor size (cm) | |||
| ≤5 | 97 (65.1) | 75 (39.1) | .000 |
| >5 | 52 (34.9) | 117 (60.9) | |
| Tumor multiplicity | |||
| Single | 84 (56.4) | 75 (39.1) | .002 |
| Multiple | 65 (43.6) | 117 (60.9) | |
| Survival state | |||
| Live | 121 (81.2) | 109 (56.8) | .000 |
| Dead | 28 (18.8) | 83 (43.2) | |
Bold values indicate statistical significance, P < .05.