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. 2019 Nov 28;25(44):6508–6526. doi: 10.3748/wjg.v25.i44.6508

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©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.

This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.

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NALT1 induced GC invasion and metastasis. A: NALT1 expression in GC cells compare to GES-1 cells; B: The expression of NALT1 in GC cells before and after transfection si-NALT1 sequence; C: Scrape motility assays were monitored for 24 h in NALT1-knockdown GC cells; D: Transwell assays were used to evaluate the role of NALT1 in invasion in NALT1-knockdown. U6 was used as a loading control in RT-PCR; In all figures, 100 × magnification was used, n = 3, ^aP < 0.05. NALT1: NOTCH1 associated with lncRNA in T cell acute lymphoblastic leukemia 1; GC: Gastric cancer; GES-1: Human normal gastric epithelial cell line.