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. 2019 Nov 28;25(44):6495–6507. doi: 10.3748/wjg.v25.i44.6495

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©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.

This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.

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Endogenous metadherin expression in colorectal cancer tissues. A: metadherin (MTDH) expression levels were investigated in 15 colorectal cancer (CRC) tissue samples and matching healthy colorectal tissue samples. Results are shown for 8 colon cancer tissues in pairs. P1 to P8 indicate patients with colon cancer. Data are presented as fold change in the expression in tumor tissues relative to expression in matching healthy colon tissues. P values were calculated using Student’s t-test (^aP < 0.05); B: Relative endogenous NFKB1 (n = 5) and RELA (n = 4) expression levels in colon cancer tissue samples and matching healthy colon tissue samples. Data are presented as fold change in the expression in tumor tissues relative to expression in matching healthy colon tissues; C: Immunostaining of MTDH in human CRC and adjacent healthy colorectal samples (200 × magnification). Experiments were independently performed three times in duplicates. MTDH: Metadherin.