Skip to main content
. Author manuscript; available in PMC: 2019 Dec 3.
Published in final edited form as: Lancet. 2016 Dec 13;389(10066):255–265. doi: 10.1016/S0140-6736(16)32517-X

Table 3: Summary of adverse events in the safety population.

Atezolizumab (n=609) Docetaxel (n=578)
All adverse events 573 (94%) 555 (96%)
 Treatment-related adverse events 390 (64%) 496 (86%)
Grade 3 or 4 adverse events 227 (37%) 310 (54%)
 Treatment-related grade 3 or 4 adverse events 90 (15%) 247 (43%)
All deaths 10 (2%) 14 (2%)
 Treatment-related death 0 1 (<1%)*
Serious adverse events 194 (32%) 181 (31%)
Adverse events leading to withdrawal from treatment 46 (8%) 108 (19%)
Adverse events leading to dose modification, delay, or interruption 152 (25%) 210 (36%)
*

One death due to a respiratory tract infection.