Table 3: Summary of adverse events in the safety population.
Atezolizumab (n=609) | Docetaxel (n=578) | |
---|---|---|
All adverse events | 573 (94%) | 555 (96%) |
Treatment-related adverse events | 390 (64%) | 496 (86%) |
Grade 3 or 4 adverse events | 227 (37%) | 310 (54%) |
Treatment-related grade 3 or 4 adverse events | 90 (15%) | 247 (43%) |
All deaths | 10 (2%) | 14 (2%) |
Treatment-related death | 0 | 1 (<1%)* |
Serious adverse events | 194 (32%) | 181 (31%) |
Adverse events leading to withdrawal from treatment | 46 (8%) | 108 (19%) |
Adverse events leading to dose modification, delay, or interruption | 152 (25%) | 210 (36%) |
One death due to a respiratory tract infection.