. Author manuscript; available in PMC: 2020 Apr 1.

Published in final edited form as: Cancer Causes Control. 2019 Feb 20;30(4):355–363. doi: 10.1007/s10552-019-01139-5

Table 3.

Association of metabolic factors according to NCEP criteria with endometrial cancer, Women’s Health Initiative

Variable	Cases N	Non-cases N	HR^a	95% CI
Metabolic syndrome (including WC)
No. of components
0	15	1,961	1.00	Ref.
1	27	3,036	1.18	0.62–2.21
2	35	2,961	1.65	0.90–3.04
3	44	2,554	2.51	1.39–4.56
4	34	1,626	3.16	1.70–5.86
5	21	747	4.31	2.99–8.49
P for trend			< 0.001
Metabolic syndrome (excluding WC)^b
No. of components
0	26	2,523	1.00	Ref.
1	43	4,023	0.88	0.54–1.45
2	47	3,310	1.09	0.66–1.80
3	34	2,107	1.16	0.68–1.98
4	26	922	1.94	1.09–3.46
P for trend			0.017

WC waist circumference

Adjusted for age, pack-years of smoking, alcohol intake, physical activity, hormone therapy ever, oral contraceptive ever, menopausal status, education, ethnicity, family history of endometrial cancer and allocation to the observational study or intervention/placebo/control arm of each clinical trial

Also adjusted for WC