Fig. 2.

Regional differences in the protocol and drug for the AVT (multiple answers were possible and, as such, the total may be > 100%). Some centers reported the use of a complex approach testing different drugs in a single patient, or use different agents according to the patient-specific diagnosis/clinical situation, or to the planned therapeutic strategy. The answers in each continent do not represent the practice in every center of that continent, but only the practice in the centers of that continent who answered the survey.