Figure 4.

Effect of UA–norfloxacin combination on generation of ROS (H₂O₂ and NO). (A) Measurement of intracellular H₂O₂ levels in MRSA‐2071 exposed to different concentrations of UA and norfloxacin alone as well as in combination. Ciprofloxacin was used as a positive control in the study. (B) Effect of UA–norfloxacin combination at variable concentrations on generation of NO levels. Sodium nitroprusside was included in the study as positive control. The tests were performed thrice and data are expressed as mean ± SEM (ns, not significant; **P < 0.01, ***P < 0.001, Dunnett's test).