NCT02011139.

Trial name or title	Cognitive‐behavioural (CBT) in ESRD patients with depression
Methods	Patients in HD were divided in CBT group and control group
Participants	Inclusion criteria Patients with ESKD on HD more than 3 months; patients with BDI‐II score ≥ 15 points; adult with age ≥ 20 years old; both genders; patients who were able to understand and willing to sign the written informed consent Exclusion criteria Patients on HD due to AKI; patients who are on admission; undergoing chemotherapy or radiation therapy due to progressive malignant disease; patients who are planning kidney transplantation within few months; with cognitive dysfunction, mental retardation, and drug addict; unavailable for adequate communication with researchers; patients who changed anti‐depressive agent or dose within 2 months before/after the trial.
Interventions	Treatment group 12 sessions of cognitive‐behavioural group therapy in the first 12 weeks Control group Usual care
Outcomes	Depression BDI‐II Hamilton Depression Rating Scale (HAMD‐17) Diagnosis of major depressive disorder (DSM‐IV) Anxiety BAI Stress Perceived Stress Scale HRQoL KDQOL WHO Quality of Life‐BREF (WHOQOL‐BREF) Anxiety BAI Stress Perceived Stress Scale HRQoL KDQOL WHO Quality of Life‐BREF (WHOQOL‐BREF) Temperament and Character Temperament and Character Inventory (TCI) Biomarker related with depression Serotonin Additional anti‐depressant use after trial
Starting date	October 2013
Contact information	C. S. Lim; Email: cslimjy@snu.ac.kr
Notes	Setting: Seoul National University Boramae Hospital, Seoul, Korea. Trial registration number: NCT02011139.