TABLE 3.
The fractional inhibitory concentration index (FICI) of the peptide/antibiotic combination against the MRSE 1208 strain.
| FICI | |||||
| Penicillin | Ampicillin | Ceftazidime | Erythromycin | Tetracycline | |
| L11W | 0.3121 | 0.2808 | 0.6248 | 0.2808 | 0.6248 |
| L12W | 0.2808 | 0.2574 | 0.6248 | 0.2808 | 0.5624 |
| I1WL5W | 0.2812 | 0.2578 | 0.5641 | 0.2812 | 0.2820 |
| I4WL5W | 0.1875 | 0.1562 | 0.5641 | 0.3124 | 0.6248 |
Synergy is defined as FICI ≤ 0.5, addition is defined as 0.5 < FICI ≤ 1.0, and indifference is defined as 1.0 < FICI ≤ 2.0 as indifference (Hollander et al., 1998; Yoon et al., 2004). Experiments were per formed in triplicate (n = 6).