Skip to main content
. Author manuscript; available in PMC: 2019 Dec 3.
Published in final edited form as: Cancer Lett. 2018 Jun 15;432:216–226. doi: 10.1016/j.canlet.2018.06.011

Fig. 5. Srx knockout mice were resistant to urethane-induced lung tumorigenesis.

Fig. 5.

(A) Schematic presentation of the urethane-induced mouse lung tumorigenesis protocol; (B) Effect of urethane on the body weight of treated mouse groups with different genotypes (Srx wildtype, +/+; heterozygous, +/−; knockout, −/−). *Compared with Srx+/+, p < 0.05 (n = 15, paired t-test). (C) Representative gross images of extracted lungs showed visible tumors on the surface. (D) Representative microscopic images of lung tumors in H&E staining. (E) The average number of lung tumors in mice with different genotypes was compared; (F) The average size of lung tumors in mice with different genotypes was compared. *Compared with Srx+/+, p < 0.05 (n = 15, t-test in both E and F).