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. Author manuscript; available in PMC: 2020 Oct 6.
Published in final edited form as: Annu Rev Cell Dev Biol. 2019 Jul 5;35:381–406. doi: 10.1146/annurev-cellbio-100818-125403

Figure 1.

Figure 1

Four core immune modules shared between ILCs, DCs, and T cells. An immune response specific to a particular pathogen involves cross talk and collaboration between two innate cell lineages, ILCs and DCs, and an adaptive cell lineage, T cells, by secretion of cytokines and chemokines. Each cell type in this module is governed by specific transcription factors that influence the effector functions. Abbreviations: cDC, classical/conventional dendritic cell; CTL, cytotoxic T lymphocyte; DC, dendritic cell; IFN, interferon; ILC, innate lymphoid cell; pDC, plasmacytoid dendritic cell.