. Author manuscript; available in PMC: 2019 Dec 3.

Published in final edited form as: Toxicol Appl Pharmacol. 2007 Jul 31;225(1):70–79. doi: 10.1016/j.taap.2007.07.009

Table 4.

Influence of G4.0 PAMAM Dendrimer Exposure Conditions on Toxicity of Zebrafish Embryos at 120 hpf

Exposure (hpf)	Toxicity Score (mean +SE)

	G4.0 Dendrimer Concentration (μM)
	0	0.2	0.5	1.0	2.0	20.0
6–120	0.1 ± 0.1	0.4 ± 0.1^a	3.1 ± 0.2^b	3.9 ±0.1^c	4.0 ± 0.0^c	4.0 ± 0.0^c
6–7.5	0.4 ± 0.3	0.7 ± 0.4^a	0.7 ± 0.3^a	1.6 ± 0.4^b	3.4 ± 0.2^c	4.0 ± 0.0^c
24–120 + chorion	0.1 ± 0.1	0.1 ± 0.1	1.9 ± 0.3^a	4.0 ± 0.0^b	4.0 ± 0.0^b	4.0 ± 0.0^b
24–120 − chorion	0.1 ± 0.1	0.2 ± 0.1	1.0 ± 0.3^a	3.3 ±0.7^b	3.9 ± 0.1^b	4.0 ± 0.0^c

Note: Letters denote dose-related effects within each experimental paradigm.