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. 2019 Nov 29;7:e8128. doi: 10.7717/peerj.8128

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© 2019 Yue et al.

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed. For attribution, the original author(s), title, publication source (PeerJ) and either DOI or URL of the article must be cited.

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(A) Volcano plot of TME-related DEGs. |log2(Fold Change)| > 1 and FDR < 0.05 were set as screening criteria. The green, red and black dots represented the down-, up-regulated TME-related DEGs and genes that were not satisfied the screening criteria, respectively. (B) The heatmap of top 10 stromal and immune signature DEGs. The stromal signature DEGs were presented in blue color and immune signature DEGs were in black. TME, Tumor microenvironment; DEGs, Differentially expressed genes; LADC, Lung adenocarcinoma.