Set #		Results
1	“plasmapheresis”[MeSH Terms] OR “plasmapheresis”[tiab] OR “plasma exchange”[tiab] OR “plasma exchange”[MeSH Terms]	19453
2	“Anticoagulants”[Pharmacological Action] OR “Anticoagulants”[Mesh] OR anticoagulant[tiab] OR anticoagulants[tiab] OR “apixaban”[Supplementary Concept] OR “apixaban”[tiab] OR “rivaroxaban”[MeSH Terms] OR “rivaroxaban”[tiab] OR “edoxaban”[Supplementary Concept] OR “edoxaban”[tiab] OR “dabigatran”[MeSH Terms] OR “dabigatran”[tiab] OR “warfarin”[MeSH Terms] OR “warfarin”[tiab] OR “enoxaparin”[MeSH Terms] OR “enoxaparin”[tiab] OR “dalteparin”[MeSH Terms] OR “dalteparin”[tiab] OR “heparin”[MeSH Terms] OR “heparin”[tiab] OR “tinzaparin”[Supplementary Concept] OR “tinzaparin”[tiab] OR “argatroban”[Supplementary Concept] OR “argatroban”[tiab] OR “bivalirudin”[Supplementary Concept] OR “bivalirudin”[tiab] OR “betrixaban”[Supplementary Concept] OR “betrixaban”[tiab] OR “ximelagatran”[Supplementary Concept] OR “ximelagatran”[tiab]	261674
3	therapy[tiab] OR therapies[tiab] OR “therapy”[Subheading] OR “therapeutic use”[Subheading] OR therapeutic[tiab]	8587273
4	#1 AND #2 AND #3	970
5	#4 AND (randomized controlled trial[pt] OR controlled clinical trial[pt] OR randomized[tiab] OR randomised[tiab] OR randomization[tiab] OR randomisation[tiab] OR placebo[tiab] OR drug therapy[sh] OR randomly[tiab] OR trial[tiab] OR groups[tiab] OR Clinical trial[pt] OR “clinical trial”[tiab] OR “clinical trials”[tiab] OR “evaluation studies”[Publication Type] OR “evaluation studies as topic”[MeSH Terms] OR “evaluation study”[tiab] OR evaluation studies[tiab] OR “intervention studies”[tiab] OR “intervention study”[tiab] OR “intervention studies”[tiab] OR “case-control studies”[MeSH Terms] OR “case-control”[tiab] OR “cohort studies”[MeSH Terms] OR cohort[tiab] OR “longitudinal studies”[MeSH Terms] OR “longitudinal”[tiab] OR longitudinally[tiab] OR “prospective”[tiab] OR prospectively[tiab] OR “retrospective studies”[MeSH Terms] OR “retrospective”[tiab] OR “follow up”[tiab] OR “comparative study”[Publication Type] OR “comparative study”[tiab] OR systematic[subset] OR “meta-analysis”[Publication Type] OR “meta-analysis as topic”[MeSH Terms] OR “meta-analysis”[tiab] OR “meta-analyses”[tiab])	425
6	#5 NOT (Editorial[ptyp] OR Letter[ptyp] OR Comment[ptyp])	418
7	#6 NOT (animals[mh] NOT humans[mh])	409
8	#7 AND (“2017/12/21”[PDAT] : “3000/12/31”[PDAT])	4