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Close-up of HiDapE bound by the products of l,l-SDAP hydrolysis, succinic acid (cyan) and l-diaminopimelic acid (yellow), and the interacting side chains and zinc ions. (A) Fo – Fc omit map of the products at 3.5σ. (B) The side chains are colored orange or green to highlight the contribution of residues in both subunits of the homodimer. Residues interacting with succinic acid and l,l-DAP are highlighted in cyan and yellow boxes, respectively.
