Table 2. Univariate and Multivariable Logistic Regression Predicting for Lymph Node Metastasis.

CARE: clear cell, angiosarcoma, rhabdomyosarcoma, and epithelioid; CI: confidence interval

Variable	Univariate Odds Ratio (95% CI)	P-value	Multivariable Odds Ratio (95% CI)	P-value
Age (Continuous)	0.993 (0.986 – 0.999)	0.043	0.99 (0.987 – 1.001)	0.087
Sex			NA
Male	Reference
Female	1.00 (0.77 – 1.30)	0.999
Race			NA
White	Reference
Black	1.20 (0.81 – 1.78)	0.355
Asian	1.18 (0.55 – 2.54)	0.668
Unknown	0.49 (0.16 – 1.56)	0.228
Location
Trunk	Reference		Reference
Extremity	0.59 (0.43 – 0.82)	0.002	0.70 (0.50 – 0.99)	0.042
Size
≤ 5 cm	Reference		Reference
> 5 cm	3.92 (1.40 – 10.93)	0.009	4.12 (1.42 – 11.99)	0.009
Unknown	2.31 (1.50 – 3.55)	< 0.001	2.41 (1.52 – 3.80)	< 0.001
Grade
I	Reference		Reference
II	6.59 (2.47 – 17.60)	< 0.001	6.05 (2.26 – 16.23)	< 0.001
III	19.03 (7.83 – 46.29)	< 0.001	15.55 (6.36 – 38.04)	< 0.001
Histology
Other	Reference		Reference
CARE	7.49 (5.44 – 10.30)	<0.001	4.72 (3.35 – 6.66)	< 0.001
Synovial	1.40 (0.74 – 2.68)	0.303	0.98 (0.50 – 1.93)	0.953
Lymphovascular Invasion
Absent	Reference		Reference
Present	10.10 (6.01 – 16.98)	< 0.001	5.86 (3.33 – 10.31)	< 0.001
Unknown	1.67 (1.17 – 2.38)	0.005	2.17 (1.43 – 3.29)	< 0.001
Neurovascular Invasion
Absent	Reference		Reference
Present	3.38 (1.51 – 7.56)	0.003	1.16 (0.47 – 2.83)	0.751
Unknown	1.20 (0.89 – 1.61)	0.245	1.71 (1.17 – 2.51)	0.006
Bone Invasion
Absent	Reference		Reference
Present	3.84 (1.96 – 7.54)	< 0.001	2.73 (1.32 – 5.61)	0.006
Unknown	0.68 (0.52 – 0.90)	0.006	0.40 (0.28 – 0.58)	< 0.001