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. Author manuscript; available in PMC: 2019 Dec 3.
Published in final edited form as: Hypertension. 2019 Oct 28;74(6):1399–1408. doi: 10.1161/HYPERTENSIONAHA.119.13398

Figure 5.

Figure 5.

Leptin reduces inflammation in lipodystrophy. Inflammatory markers in thoracic aorta measured by real-time polymerase chain reaction (RT-PCR; A) and IL (interleukin)-1β plasma levels (B) from gBscl2+/+ or gBscl2−/− (Berardinelli-Seip 2 gene–deficient) mice treated or not with leptin (10 μg/d for 7 d; osmotic mini-pump). Data are presented as means±SEM. RT-PCR graph is presented as interleaved from minimal to maximal. *P<0.05 vs gBscl2+/+; †P<0.05 vs gBscl2−/−. n=4 to 6. Two-way ANOVA test followed by Tukey multiple comparison test was used for comparison between 4 groups. FOxP3 indicates forkhead box P3; IL-1 Interleukine 1B; and TNF-α, tumor necrosis factor-α.