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. Author manuscript; available in PMC: 2020 Oct 1.
Published in final edited form as: J Orthop Res. 2019 Jul 26;37(10):2122–2129. doi: 10.1002/jor.24396

Figure 4. Influence of neonatal Abx on bone tissue material properties.

Figure 4.

Figure 4.

Figure 4.

Figure 4.

Figure 4.

Figure 4.

(A) Tissue mineral density in distal femur secondary spongiosa; n=5–11 male or 18–26 female mice per condition.

(B) Tissue mineral density in midshaft femur; n=5–10 male or 6–17 female mice per condition.

(C) Hydroxyapatite-calibrated heatmap of tissue mineral density distribution in mid-diaphyseal cortical bone from male and female mice gavaged with water or neonatal Abx.

(D) Histograms of mid-diaphyseal TMDD quantification. (i) Diagrammatic representation of CaPEAK, CaMEAN, and CaWIDTH; TMDD in (ii) male and (iii) female mice.

Columns represent mean ± standard deviation; groups with different letters are statistically different from each other.