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. 2019 Dec 2;14(12):e0224517. doi: 10.1371/journal.pone.0224517

Fig 7. Macmoondongtang dose-dependently suppressed Th2-related cytokines such as IL-4, IL-5, and IL-13.

Fig 7

Macmoondongtang significantly and effectively inhibited the gene expression of IL-5 (A) and IL-5 protein level (C). The treatment dose-dependently controlled the IL-4 protein expression (B). Similar changes at the gene (A) and protein levels of IL-13 (D) were observed as those for IL-5. a, vehicle control; b, asthma induction; c, dexamethasone; d,150 mg/kg/day macmoondongtang; e, 1500 mg/kg/day macmoondongtang. Each bar represents the mean ± SD (n = 8). *p < 0.05 vs. control; **p < 0.001 vs. control; $p < 0.05 vs. asthma induction; #p < 0.05 vs. dexamethasone. Scale Bar = 50 μm. Magnification, ×200.