Table 2. Multivariate linear regression analysis of the association between CRP levels on POD1 and preoperative and intraoperative variables in training cohort.

Variables	β	P
Age (years)	-0.003	0.9640
Sex (M/F)	-0.077	0.1538
BMI	-0.043	0.4209
ASA-PS (I/II)	0.058	0.2947
Duration of surgery (min)	0.297	<0.0001**
Mean NR	0.120	0.0347*
Preoperative CRP level (mg•dL-1)	0.139	0.0091**

Data are presented as standardized beta coefficient (β). ASA-PS: American Society of Anesthesiologists physical status, BMI: body mass index, CRP: C-reactive protein, NR: nociceptive response, POD: postoperative day.

*P<0.05 and

**P<0.01 are significant.