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. 2019 Dec 2;14(12):e0225651. doi: 10.1371/journal.pone.0225651

Table 2. The impact of prior weight.

Prior weight Number of prior edges Selection probability per edge in one run+ Probability of one prior edge remaining in final network by chance++ Expected number of prior edges remaining in final network by chance Number of prior edges remaining in final network P-value
1 269 0.537 4.67E-15 1.26E-12 14 9.98E-178*
2 122 0.735 3.85E-05 4.69E-03 4 1.92E-11*
3 67 0.808 9.39E-03 6.29E-01 6 4.19E-05*
4 42 0.834 4.53E-02 1.90 10 1.41E-05*
5 20 0.844 7.53E-02 1.50 4 5.90E-02
6 16 0.848 8.99E-02 1.43 4 4.94E-02*
7 6 0.849 9.59E-02 5.75E-01 0 1
> = 8 53 ≈0.850 ≈9.81E-02 ≈5.20 8 ≈1.44E-01

+ Selection probability per edge in one run = 0.85(1-e—prior weight).

++ Assuming the reliability cutoff is 90, which means one prior network should be appear at least 90 times out of 100 runs. The probability is calculated based on binomial distribution.

* Statistical significance (P-value <0.05).