Table 3. Top hub genes in prior and final networks.
| Prior network* | Final network | ||||||
|---|---|---|---|---|---|---|---|
| Gene | No. of direct neighbors | No. of children** | No. of parents** | Gene | No. of direct neighbors | No. of children | No. of parents |
| STAT1** | 59 | 34 | 25 | IRF1 | 25 | 25 | 0 |
| IRF1 | 53 | 30 | 23 | FAM72C | 21 | 0 | 21 |
| DDX58 | 40 | 17 | 23 | PDIA4 | 16 | 15 | 1 |
| FAS | 38 | 11 | 27 | JAK2 | 15 | 15 | 0 |
| PML | 32 | 21 | 11 | SLFN12 | 15 | 1 | 14 |
| CXCL10 | 31 | 11 | 20 | GALM | 15 | 1 | 14 |
| TNFSF10 | 30 | 17 | 13 | DHRS9 | 15 | 0 | 15 |
| CCL2 | 28 | 8 | 20 | STAT1 | 13 | 13 | 0 |
| IRF7 | 28 | 15 | 13 | HCG26 | 13 | 0 | 13 |
| CASP1 | 25 | 10 | 15 | STAT2 | 11 | 10 | 1 |
| PLK1 | 24 | 13 | 11 | IRF7 | 11 | 4 | 7 |
| IFIH1 | 22 | 10 | 12 | RBM43 | 11 | 0 | 11 |
Genes are sorted based on the number of direct neighbors
* Prior information includes bi-directed edges.
** The common genes in both lists are in bold.