Table 1. Identification of components of phagocytosis and TLRs in phagosome-containing fractions of human monocyte derived macrophages.
ND, not detected. PSM: Protein Spectra Matching; SAF: Spectral Abundance Factor; NSAF: Normalized Spectral Abundande Factor.
| Uniprot ID | Description | Fraction # | Σ Coverage | Σ# Proteins | Number of Unique Peptides | Number of Total Peptides | Σ# PSMs | SAF | NSAF |
|---|---|---|---|---|---|---|---|---|---|
| ITAM_HUMAN | Integrin alpha-M | 4 | 16.49 | 1 | 14 | 15 | 41 | 0.3226 | 0.1322 |
| 6 | 23.78 | 1 | 21 | 22 | 57 | 0.4485 | 0.0746 | ||
| 8 | 17.71 | 1 | 15 | 16 | 43 | 0.3383 | 0.0707 | ||
| ITB2_HUMAN | Integrin beta-2 | 4 | 37.58 | 1 | 24 | 25 | 83 | 0.9796 | 0.4016 |
| 6 | 44.47 | 1 | 26 | 27 | 125 | 1.4753 | 0.2455 | ||
| 8 | 40.96 | 1 | 26 | 27 | 96 | 1.1331 | 0.2368 | ||
| CD14_HUMAN | Monocyte differentiation antigen CD14 | 4 | 22.40 | 1 | 8 | 8 | 32 | 0.7990 | 0.3275 |
| 6 | 32.80 | 1 | 10 | 10 | 67 | 1.6729 | 0.2784 | ||
| 8 | 32.80 | 1 | 10 | 10 | 47 | 1.1735 | 0.2452 | ||
| TLR2_HUMAN | Toll-like receptor 2 | 4 | 13.65 | 1 | 10 | 10 | 32 | 0.3564 | 0.1461 |
| 6 | 24.74 | 1 | 15 | 15 | 58 | 0.6460 | 0.1075 | ||
| 8 | 14.80 | 1 | 10 | 10 | 33 | 0.3676 | 0.0768 | ||
| TLR8_HUMAN | Toll-like receptor 8 | 4 | 3.94 | 1 | 4 | 4 | 4 | 0.0334 | 0.0137 |
| 6 | 8.74 | 1 | 9 | 9 | 14 | 0.1169 | 0.0195 | ||
| 8 | 7.01 | 1 | 7 | 7 | 9 | 0.0752 | 0.0157 | ||
| TLR6_HUMAN | Toll-like receptor 6 | 4 | 1.63 | 1 | 1 | 1 | 2 | 0.0218 | 0.0089 |
| 6 | ND | ND | ND | ND | ND | ND | ND | ||
| 8 | ND | ND | ND | ND | ND | ND | ND | ||
| TLR5_HUMAN | Toll-like receptor 5 | 4 | 0.93 | 1 | 1 | 1 | 1 | 0.0102 | 0.0042 |
| 6 | ND | ND | ND | ND | ND | ND | ND | ||
| 8 | ND | ND | ND | ND | ND | ND | ND | ||
| CD180_HUMAN | CD180 Antigen | 4 | 2.42 | 1 | 1 | 1 | 1 | 0.0135 | 0.0055 |
| 6 | 8.47 | 1 | 4 | 4 | 7 | 0.0944 | 0.0157 | ||
| 8 | 2.42 | 1 | 1 | 1 | 2 | 0.0270 | 0.0056 |