Table 2. Parameters used in the stochastic simulation.
Reaction | Parameter | Description | Range for parameter search (h-1) |
---|---|---|---|
Transition | k1 | Off to On | 0.25 to 2.5 |
k2 | On to Off | 0.01 to 10 | |
k3 | On to On-Tax | 0.1 to 10 | |
k4 | On-Tax to On | 0.01 to 10 | |
k10 | On-Tax to Off | 0.01 to 10 | |
Transcription | k5 | From On state | 10 to 50 |
k6 | From On-Tax state | k5 to 100 | |
Translation | k8 | Tax translation | 0.01 to 10 |
Degradation | k7 | Sense mRNA | 0.154 (fixed) |
k9 | Tax protein | 0.105 (fixed) |