Table 1:

Selected IVIM studies of normal brain and their respective reported IVIM parameters.

Study	Brain Region	Number of Subject	b factor	Age Range	Sex	Voxel Size	D*/D	D*(*10–3 μm2/ms)	f
Faderau et. al. 2012	Full Brain	7	16 b value: 0 to 900 s/mm2	mean: 27	5 males; 2 females	1.16 × 1.16 × 4.0 mm3	7.93	7.14	0.061
Faderau et. al. 2013	Full Brain excluding CSF
	Systole	20	16 b value: 0 to 900 s/mm2	mean: 24	10 males; 10 females	1.0 × 1.4 × 5.0 mm3	14.74	11.5	0.073
	Diastole						11.8	9.2	0.07
Finkenstaedt et. al. 2017	Grey Matter	9	37 different b value: 0 to 1300 s/mm2	mean: 34; range: 22–64	6 males; 3 females	2 × 2 × 2 mm3	6.84	6.22	0.1
Here et. Al. 2017	Grey Matter	10	16 b value: 0 to 900 s/mm2			3.4 × 3.4 × 6 mm3	12.93	11.77	0.11
Meeus et. al. 2018	Grey Matter	16	3 b value: 0, 300,1000 s/mm2	mean: 26; range: 25–30		2.5 × 2.5 × 3.5 mm3			0.104
			3 b value: 0, 500,1000 s/mm2						0.141
Reischauer & Gutzeit 2017	Grey Matter	1	12 b value: 0 to 1000 s/mm2			1.57 × 1.57 × 5.0 mm3	10.13	7.7	0.11
	White Matter						10	7.2	0.07
Rydhög et. al. 2017	Comprehensive WM Protocol + JHU DTI-based atlas ROIs	1	44 b value: 0 to 800 s/mm2	30	male	1.3 × 1.3 × 4.0 mm3			0.024
		1		33	male				0.049
			5 b value: 0 to 1400 s/mm2
	Clinical WM Protocol + JHU DT1-based atlas ROIs
						2.5 × 2.5 × 2.5 mm3
Spinner et. al. 2018	Full Brain excluding CSF	11	16 b value: 0 to 900 s/mm2	mean: 27	3 males; 8 females	1.2 × 1.2 × 5 mm3	8.73	6.9	0.0846
Wirestam et. al. 2001	Thalamus	56	36 different b value: 0 to 1200 s/mm2	mean: 68.5; range: 45–83	17 males; 11 females	1.95 × 1.25 × 10 mm3		14	0.11
	Frontal WM	54						21	0.076
	All ROIs:	110						17	0.093
Wirestam et. al. 1997	Healthy Control WM	5	37 different b value: 0 to 1200 s/mm2	range: 25–32		1.95 × 1.25 × 8 mm3			0.045