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. 2019 Nov 25;9(11):e031414. doi: 10.1136/bmjopen-2019-031414

Table 2.

The associations between CVH score and CVD-related biomarkers

Total, n=5379
hsCRP
(mg/L)
D-dimer
(μg/mL)
Fibrinogen
(mg/dL)
Homocysteine
(μmol/L)
hs-cTnT
(ng/L)
NT-ProBNP
(pg/mL)
IL-6*
(pg/mL)
Model 1 0.16
(−0.17,−0.14)
0.06
(−0.07,−0.05)
0.02
(−0.03,−0.02)
0.02
(−0.02,−0.01)
0.05
(−0.06,−0.05)
0.00004
(−0.01, 0.01)
0.09
(−0.10,−0.08)
Model 2 0.13
(−0.14,− 0.12)
0.03
(−0.04,−0.02)
0.02
(−0.02,−0.02)
0.01
(−0.01,−0.01)
0.04
(−0.05,−0.03)
0.02
(0.01,0.03)
0.07
(−0.08,−0.06)
Women, n=2775
Model 1 0.18
(−0.20,−0.16)
0.07
(−0.09,−0.06)
0.03
(−0.03,−0.03)
0.02
(−0.03,−0.02)
0.04
(−0.05,− 0.04)
0.01
(−0.01,0.03)
0.11
(−0.12,−0.10)
Model 2 0.16
(−0.18,−0.14)
0.03
(−0.05,−0.02)
0.02
(−0.03,−0.02)
0.01
(−0.02,−0.01)
0.03
(−0.04,−0.02)
0.03
(0.01,0.04)
0.08
(−0.09,−0.07)
Men, n=2604
Model 1 0.13
(−0.15,−0.11)
0.04
(−0.05,−0.02)
0.02
(−0.02,−0.02)
0.01
(−0.02,−0.01)
0.07
(−0.08,−0.06)
−0.01
(−0.03, 0.01)
0.07
(−0.08,−0.06)
Model 2 0.10
(−0.12,−0.08)
0.02
(−0.03,−0.001)
0.02
(−0.02,−0.01)
0.01
(−0.01,−0.004)
0.06
(−0.07,−0.05)
0.005
(−0.01, 0.02)
0.05
(−0.06,−0.04)

*For IL-6, total sample size = 5279; women, n = 2733; men, n = 2546.

CVD, cardiovascular disease;CVH, cardiovascular health; hsCRP, high-sensitivity C-reactive protein; hs-cTnT, high-sensitivity cardiac troponin T; IL-6, interleukin 6; NT-proBNP, N-terminal pro B-type natriuretic peptide.