Table 1.
Characteristics of study participants
| Non-DED | DED | P value | Total | |
| n=57 | n=152 | n=209 | ||
| Age, year±SD | 61.4±15.5 | 57.9±15.2 | 0.149 | 58.9±15.3 |
| Gender, female (%) | 48 (84.2) | 127 (83.6) | 1.000 | 175 (83.7) |
| BCVA, logMAR±SD | −0.1±0.0 | −0.1±0.0 | 0.513 | −0.1±0.0 |
| IOP, mm Hg±SD | 14.6±2.9 | 13.8±2.7 | 0.062 | 14.0±2.8 |
| Subjective symptoms, yes (%) | 5 (8.8) | 152 (100) | ***<0.001 | 157 (75.1) |
| J-OSDI, 0–100±SD | 19.4±16.0 | 37.7±22.2 | ***<0.001 | 32.7±29.7 |
| DEQS, 0–100±SD | 16.0±14.7 | 32.7±21.6 | ***<0.001 | 28.1±21.3 |
| TFBUT, s±SD | 2.5±2.4 | 1.5±0.8 | ***<0.001 | 1.7±1.5 |
| CFS, 0–9±SD | 2.8±2.5 | 3.3±2.6 | 0.192 | 3.2±2.6 |
| Schirmer I, mm±SD | 7.2±8.2 | 5.7±6.2 | 0.162 | 6.1±6.8 |
| MBI, s±SD | 15.1±8.1 | 10.5±6.3 | ***<0.001 | 11.7±7.1 |
P values were determined using the Student’s t-test (two-tailed) for continuous variables and the χ2 test for categorical variables.
***p<0.001.
BCVA, best-corrected visual acuity; CFS, corneal fluorescein staining;DED, dry eye disease; DEQS, Dry Eye-Related Quality-of-Life Score; IOP, intraocular pressure; J-OSDI, Japanese version of Ocular Surface Disease Index; MBI, maximum blink interval; TFBUT, tear film breakup time.