Table 2.
Frequency, percentage and age-standardised rate of comorbidities in people with OA
| Comorbidity | n | % of OA cohort | % of the OA cohort with one or more of the eight comorbidities | Age standardised rate (per 1000 population) | ||
| Female (95% CI) | Male (95% CI) | SRR (95% CI) | ||||
| Comorbid conditions | ||||||
| Hypertension | 144 453 | 29.0 | 53.1 | 162.2 (160.9 to 163.5) | 146.5 (145.1 to 148.0) | 1.11 (1.09 to 1.12) |
| Depression | 99 103 | 19.9 | 36.5 | 264.1 (260.9 to 267.3) | 152.6 (149.8 to 155.4) | 1.73 (1.69 to 1.77) |
| Chronic obstructive pulmonary disease | 92 273 | 18.6 | 33.9 | 195.9 (193.0 to 198.8) | 153.6 (150.9 to 156.3) | 1.28 (1.25 to 1.30) |
| Diabetes | 47 102 | 9.5 | 17.3 | 53.1 (52.0 to 54.2) | 59.4 (58.4 to 60.4) | 0.89 (0.87 to 0.92) |
| Congestive heart failure | 27 905 | 5.6 | 10.3 | 24.4 (23.9 to 24.9) | 25.4 (24.9 to 26.0) | 0.96 (0.93 to 0.99) |
| Peripheral vascular disease | 15 044 | 3.0 | 5.5 | 12.6 (12.1 to 13.0) | 17.8 (17.2 to 18.3) | 0.71 (0.67 to 0.74) |
| Myocardial infarction | 4969 | 1.0 | 1.8 | 4.3 (4.1 to 4.5) | 4.7 (4.4 to 5.0) | 0.91 (0.84 to 0.98) |
| Cerebrovascular disease | 5974 | 1.2 | 2.2 | 4.0 (3.8 to 4.2) | 7.9 (7.6 to 8.2) | 0.51 (0.48 to 0.54) |
| No of comorbidities | ||||||
| One comorbidity | 161 315 | 32.4 | 59.4 | 329.1 (325.7 to 332.4) | 271.5 (268.2 to 274.8) | 1.21 (1.19 to 1.23) |
| Two comorbidities | 72 567 | 14.6 | 26.7 | 124.9 (122.8 to 127.1) | 84.6 (82.9 to 86.2) | 1.48 (1.44 to 1.52) |
| Three or more comorbidities | 37 912 | 7.6 | 13.9 | 42.3 (41.4 to 43.2) | 36.9 (36.2 to 37.7) | 1.15 (1.11 to 1.18) |
| OA with comorbidities | 271 794 | 54.6 | 496.3 (492.8 to 499.8) | 392.9 (389.4 to 396.4) | 1.26 (1.25 to 1.28) | |
| None of the 8 comorbidities | 225 568 | 45.4 | 503.7 (500.17 to 507.22) | 607.1 (603.56 to 610.56) | 0.83 (0.82 to 0.84) | |
% of OA cohort was calculated using OA population (271 794+225 568 = 497 362) as denominator and the population of each comorbidity as numerator. % of the OA cohort with one or more of the eight comorbidities was calculated using population with at least one comorbidity (n=271 794) as denominator. SRR denotes standardised rate ratio between females and males (females/males). The eight comorbidities are those with validated case definitions for administrative health data.
OA, osteoarthritis.