Table 3.

Frequency of top 10 common groupings of comorbidities

Combinations of comorbidity	n	% of OA cohort	% of OA with comorbidities
Hypertension only	63 520	12.8	23.4
Depression only	46 226	9.3	17.0
Chronic obstructive pulmonary disease only	34 464	6.9	12.7
Hypertension, depression	14 609	2.9	5.4
Hypertension, chronic obstructive pulmonary disease	13 653	2.7	5.0
Depression, chronic obstructive pulmonary disease	13 584	2.7	5.0
Hypertension, diabetes	11 784	2.4	4.3
Diabetes	11 054	2.2	4.1
Hypertension, depression, chronic obstructive pulmonary disease	5262	1.1	1.9
Hypertension, congestive heart failure	3946	0.8	1.5

% of OA cohort was calculated using OA population (271 794+225 568 = 497 362) as denominator and the population of each comorbidity as numerator. % of OA with comorbidities was calculated using population with at least one comorbidity at the diagnosis of OA (n=271 794) as denominator.

OA, osteoarthritis.