Table 3.
2005 | 2010 | 2015 | |||||||
Rate (95% CI) | IRR (95% CI) | P value | Rate (95% CI) | IRR (95% CI) | P value | Rate (95% CI) | IRR (95% CI) | P value | |
London | |||||||||
Overall | 139 (123 to 155) | — | — | 309 (285 to 332) | — | — | 243 (223 to 264) | — | — |
Age | |||||||||
16–44 | 216 (189 to 242) | 1 | <0.0001 | 479 (440 to 517) | 1 | <0.0001 | 327 (295 to 360) | 1 | <0.0001 |
>=45 | 39 (26 to 52) | 0.18 (0.13 to 0.26) | 93 (74 to 112) | 0.19 (0.16 to 0.24) | 150 (127 to 173) | 0.46 (0.38 to 0.55) | |||
Ethnicity | |||||||||
White | 120 (100 to 140) | 1 | <0.0001 | 270 (239 to 301) | 1 | <0.0001 | 170 (144 to 195) | 1 | <0.0001 |
Asian | 199 (117 to 280) | 1.65 (1.09,2.51) | 261 (183 to 339) | 0.97 (0.70 to 1.33) | 190 (126 to 254) | 1.12 (0.78 to 1.62) | |||
Black African | 415 (234 to 596) | 3.46 (2.21 5.43) | 825 (602 to 1048) | 3.06 (2.29 to 4.08) | 728 (527 to 929) | 4.30 (3.13 to 5.87) | |||
Black Caribbean | 248 (96 to 400) | 2.06 (1.15 to 3.72) | 438 (260 to 617) | 1.63 (1.06 to 2.48) | 399 (221 to 578) | 2.35 (1.50 to 3.70) | |||
Patient IMD (2015)* | |||||||||
Quintile 1 | 153 (112 to 194) | 1 | 0.0278 | 172 (130 to 215) | 1 | <0.0001 | 156 (115 to 197) | 1 | <0.0001 |
Quintiles 2,3,4 | 125 (106 to 143) | 0.82 (0.60 to 1.10) | 284 (258 to 311) | 1.65 (1.27 to 2.14) | 195 (173 to 218) | 1.25 (0.95 to 1.66) | |||
Quintile 5 | 183 (138 to 227) | 1.19 (0.84 to 1.71) | 539 (463 to 615) | 3.13 (2.37 to 4.14) | 520 (448 to 592) | 3.33 (2.50 to 4.46) | |||
Outside London | |||||||||
Overall | 67 (62 to 71) | — | — | 117 (111 to 123) | — | — | 83 (78 to 89) | — | — |
Age | |||||||||
16–44 | 118 (108 to 127) | 1 | <0.0001 | 216 (204 to 229) | 1 | <0.0001 | 160 (148 to 171) | 1 | <0.0001 |
>=45 | 21 (17,24) | 0.18 (0.15 to 0.21) | 34 (29 to 38) | 0.16 (0.14 to 0.18) | 29 (25 to 33) | 0.18 (0.16 to 0.21) | |||
Ethnicity | |||||||||
White | 67 (61 to 72) | 1 | <0.0001 | 117 (110 to 125) | 1 | <0.0001 | 77 (71 to 83) | 1 | <0.0001 |
Asian | 188 (123 to 252) | 2.82 (2.01 to 3.95) | 357 (284 to 430) | 3.04 (2.46 to 3.77) | 207 (155 to 259) | 2.69 (2.07 to 3.50) | |||
Black African | 515 (270,) | 7.33 (4.77 to 12.53) | 829 (563 to 1094) | 7.07 (5.13,9.73) | 432 (249 to 616) | 5.63 (3.71 to 8.53) | |||
Black Caribbean | 235 (61 to 409) | 3.53 (1.68 to 7.44) | 778 (468 to 1087) | 6.63 (4.49 to 9.79) | 489 (257 to 721) | 6.36 (3.93 to 10.30) | |||
Patient IMD (2015)* | |||||||||
Quintile 1 | 64 (54 to 73) | 1 | 0.0001 | 95 (84 to 106) | 1 | <0.0001 | 71 (61 to 81) | 1 | <0.0001 |
Quintiles 2,3,4 | 61 (55 to 67) | 0.97 (0.81 to 1.15) | 95 (88 to 102) | 1.00 (0.87 to 1.15) | 72 (65 to 78) | 1.01 (0.86 to 1.19) | |||
Quintile 5 | 92 (77 to 107) | 1.45 (1.17 to 1.79) | 241 (218 to 265) | 2.54 (2.19 to 2.95) | 152 (134 to 170) | 2.15 (1.80 to 2.57) | |||
Urban/rural class | |||||||||
Conurbation | 54 (45 to 64) | 1 | 0.0078 | 165 (148 to 181) | 1 | <0.0001 | 120 (106 to 133) | 1 | <0.0001 |
City/town | 72 (66 to 78) | 1.33 (1.10 to 1.60) | 108 (101 to 116) | 0.66 (0.59 to 0.74) | 77 (70 to 83) | 0.64 (0.56 to 0.74) | |||
Rural | 62 (50 to 74) | 1.15 (0.89 to 1.47) | 85 (71 to 99) | 0.52 (0.43 to 0.62) | 60 (48 to 72) | 0.50 (0.40 to 0.62) |
*1=least deprived - 5=most deprived.
IMD, Index of Multiple Deprivation; IRR, incidence rate ratio.