Figure 4. a. MMP-9 immunostaining (defect group). Positive MMP-9 expression in inflammatory cells, fibroblast cells, and degenerated collagen fibril areas (yellow arrow). b. MMP-9 immunostaining (defect and graft group). Positive MMP-9 reaction in fine collagen fibrils around blood vessels (yellow arrows). c. MMP-9 immunostaining (defect, graft, and Ganoderma lucidum treated group). Positive MMP-9 expression in bone matrix and collagen fibrils (yellow arrows) with the maturation of bone trabeculae. Scale bar=50 μm.
