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. Author manuscript; available in PMC: 2019 Dec 3.
Published in final edited form as: Cell Rep. 2019 Oct 8;29(2):495–510.e6. doi: 10.1016/j.celrep.2019.08.089

Figure 2. Fetal Mammary Cells at E18 Show Epigenetic Features of Partial Lineage Specification.

Figure 2.

(A) Single-cell basal-to-luminal score overlaid on the snATAC t-SNE plot. Cell cluster identities are shown.

(B) Approach to generating an aggregate snATAC profile based on single-cell clustering.

(C) Signal tracks of the aggregate snATAC profile. Signal ranges are shown in the parentheses.

(D) PCA comparing the aggregate snATAC profile with bulk ATAC-seq of sorted mammary populations. Arrows indicate putative mammary differentiation paths.

See also Figure S4.